Prevalence and Factors Associated with Histological Chorioamnionitis Among Mothers with Premature Rupture of Membranes Delivering at Three Tertiary Hospitals, Uganda
| dc.contributor.author | Abdinasir Abdi Ibrahim | |
| dc.date.accessioned | 2026-09-03T13:15:21Z | |
| dc.date.available | 2026-09-03T13:15:21Z | |
| dc.date.issued | 2024-02 | |
| dc.description.abstract | Background: Histological chorioamnionitis (HCA) unlike clinical chorioamnionitis continues to be a silent major threat to the mother and fetus all over the world. A few reports emerging from different scholars have shown that this terrifying obstetric complication is growing steadily across the world, worse in the resource constrained countries. Information regarding its magnitude, common patterns and associated factors remains extremely scanty in most of the African countries, including Uganda. Aim: To determine the prevalence and factors associated with HCA among mothers with premature rupture of membranes (PROM) delivering at three tertiary hospitals in Uganda Methods: This cross-sectional investigation was carried out at three tertiary hospitals in Uganda in a period of 3 months from July 9th to October 9th 2023 involving 106 women with PROM. Data was collected by the use of questionnaires. Binary logistic regression was used after descriptive statistics, and these were done in order to achieve the study objectives using STATA14. Results: Out of the 106 patients with PROM that were considered for the study at the three tertiary hospitals, 44(42%) had HCA. The most common histological finding was Neutrophil infiltration, 22(50.0%) followed by funisitis, 13(29.6%). Referred status (OR=4.5, 95%CI: 1.511-13.315, p=0.007) and prenatal care attendance (OR=9.8, 95%CI: 2.802-14.504, p=0.000) were discovered to be connected separately with HCA at the three tertiary hospitals in Uganda. Conclusions and recommendations: The prevalence of HCA was high compared to prior reports in Uganda. Placental infarcts are the most common histological lesions. PROM patients referred from other health centers and those who have not attended PNC are likely to have HCA. Routine screening of all women with PROM for HCA is recommended. PROM patients referred from other health centers and women who have not attended PNC should be initiated on treatment for chorioamnionitis till ruled out. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12493/15007 | |
| dc.language.iso | en | |
| dc.publisher | Kampala International University; Faculty of Cinical Medicine and Dentistry | |
| dc.title | Prevalence and Factors Associated with Histological Chorioamnionitis Among Mothers with Premature Rupture of Membranes Delivering at Three Tertiary Hospitals, Uganda | |
| dc.type | Thesis |